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By synthesizing a molecule that could permeate the cell membrane and selectively inhibit NNMT, researchers discovered they could fundamentally alter the metabolic profile of the cell

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PMID 10448529

The reason: since the fragment contains only the C-terminal part, it lacks the binding domains for GHR (most of the affinity of hGH for GHR lies in the central part of the molecule)

Formestane is a newer AI used as an injection solution and is not widely available in the athletic community (Llewellyn, 2017)

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