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& Miwa, J

Even trace amounts of metal ions from the rubber stopper or glass vial can catalyze oxidation reactions over time

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Via UBA, P63 containing the LIR or GIM structure domain attaches to ubiquitinated protein aggregates, mitochondria, etc., and the LIR or GIM structural domain binds to LC3 or GABARAP on the autophagy membrane and then forms autophagosomes