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The intake of capsules containing 500 mg of curcumin powder (1500 mg per day) for 12 weeks significantly decreases glucose and DHEA levels in patients with PCOS11

Although the exact mechanisms have not been elucidated in pathogenesis of autoimmune ILDs, macrophages being the chief cells of innate immunity, are involved in exaggerated inflammatory response, defective efferocytosis, presenting self antigens, and releasing profibrotic cytokines and chemokines

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341 BSO, a gamma-glutamylcysteine synthetase inhibitor, disrupts redox balance and sensitizes cancer cells to chemotherapy, 342 while Imexon generates ROS, causing DNA damage and apoptosis in multiple myeloma