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For example, the ingestion of trimethylamine-containing (TMA-containing) dietary nutrients enriched in animal products such as choline, phosphatidylcholine, and l-carnitine can serve as precursor for the ultimate generation of an atherogenic metabolite, trimethylamine N -oxide (TMAO), via a metaorganismal pathway involving initial gut microbial formation of TMA, followed by host hepatic conversion of TMA into TMAO (48)

Choline Bitartrate

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Eur J Pharmacol 296 : 129136 Parnetti L, Gaiti A, Mecocci P, Cadini D, Senin U

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[3] L-carnitine dosage : Typical supplemental doses range from 500mg to 2,000mg daily , though some studies have used up to 3,000mg