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7.2.3 Studies of underlying mechanisms Elucidating the molecular interactions among agents used in combination therapy is essential for optimizing dose selection, minimizing adverse effects, and avoiding mechanistic redundancy

Inrig JK, Barnhart HX, Reddan D, et al

IL-1 and TGF- induce the transition of mesothelial cells to apCAFs

Research suggests that this is even more important for women who are pregnant or lactating (6)

Clin Exp Immunol 191:279287

Starting peptides individually before combining helps identify which causes any effects experienced
