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What the best clinical evidence shows about B12 injections and weight loss For people without a documented deficiency, the best human clinical data do not support B12 injections as a reliable method for weight loss

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NN8022-1807 Study Group

A 2024 study found deficiency prevalence ranges from 5% to 52% in vegans, with the wide gap reflecting differences in supplement use

Any suspected side effects from these or any other medicines or research chemicals should be reported to the MHRA via the Yellow Card Scheme at yellowcard.mhra.gov.uk

Mild injection site reactions (redness, tenderness) were the most common reported effects, and these typically resolved within days of continued use