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Cytometry A 2007

The peptide still functions

Women with PCOS have higher levels of androgen, which enhances the development of male traits, such as extra hair growth, oily skin, and acne

GCL is specific for the glutamyl moiety and is regulated physiologically by: (a) nonallosteric feedback competitive inhibition by GSH (K i =2.3mM) which involves binding of GSH to the glutamate and another site on the enzyme (Richman and Meister, 1975

Noriega et al

Strep-MBP-ROXY9-CCLS, which lacks the resolving cysteine, became glutathionylated most likely at both cysteines of the CCLS signature upon GSSG treatment (Fig
