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Cryotherapy has shown promise, with existing studies suggesting both local and whole-body cryotherapy provide pain relief and improvement in VAS scores

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In humans, the same effect was seen with restriction of carbohydrates rather than full calorie restriction

Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis

Opioids are frequently co-prescribed with benzodiazepines, compounding the risk of adverse outcomes, including falls and potential overdose fatalities