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Recent research has indicated that wild-type p53 can promote ferroptosis in certain contexts (e.g., by repressing SLC7A11), whereas selected gain-of-function mutants may also sensitize tumor cells to ferroptosis, although many mutants confer resistance (70)

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PER-TDT peaked approximately 8 hr after the 3 69-VNP peak in the LNvs and DN1s, recapitulating the characteristic lag between per mRNA and protein accumulation 29

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Among the identified genes, we found a decrease in GPX4 among the ferroptosis-associated DEGs in dopaminergic neurons

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Lets Sum Up In conclusion, it is crucial to understand the symptoms and effects of glutathione deficiency on our overall health

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Tsunemi T, Ishiguro Y, Yoroisaka A et al (2020) Astrocytes protect human dopaminergic neurons from -synuclein accumulation and propagation

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Longevity research groups: Interested in NAD+-related anti-aging interventions

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