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In addition, it resulted in a 2.84% rise in elasticity, a 15.65% increase in denseness, a 5.83% increase in moisture content, a 0.79% increase in lightness, and a 5.43% increase in ITA (a skin color index) [135]

The reason for this phenomenon may be that the LDL receptor-related proteins mainly mediate lipoprotein clearance by the liver when LDL receptors are absent, while the lack of apoE prevents the normal diet-induced increase of very-low-density lipoprotein (VLDL) production [58, 59]

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Hesperetin nanocrystals improve mitochondrial function in a cell model of early Alzheimer disease

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Cavaletti G, Alberti P, Argyriou AA, Lustberg M, Staff NP, Tamburin S, et al