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While stress and lifestyle can play a role, ongoing fatigue is often linked to vitamin B12 deficiency , a condition that affects many adults in the UK

In experimental contexts, DSIP is investigated for its involvement in neurochemical signalling, endocrine pathway regulation, and stress-response mechanisms

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Substantial evidence shows that some miRNAs (such as miR-1, miR-206, and miR-148a-3p) can suppress the proliferation, survival, invasion, and metastasis of ovarian cancer cells by directly targeting c-Met, and subsequently regulating downstream signaling pathway to serve as tumor suppressors such as PI3K/Akt/mTOR and ERK1/2 pathways (Qu et al., 2017