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In AD patients, vitamin deficiencies are typical phenomena

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4 The factorial Kruskal-Wallis test was employed to calculate LDA Effect Size, with an alpha value of 0.05 for the test among classes

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At the same time, abnormal renal biosynthesis of l-arginine (a NO substrate) and increased production of asymmetric dimethylarginine (an endogenous inhibitor of NO synthase) can lead to decreased production of NO and ultimately ED (Baylis 2006)