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Stopping GLP-1 receptor agonists 14 days prior to total hip or knee arthroplasty may reduce several key risk factors associated with anesthesia complications, according to results presented here.“Specifically for semaglutide, stopping that medication 14 days before surgery is safest based upon the dataset that we have to minimize your risks with anesthesia, especially when

Various GLP-1RAs have been demonstrated to have significant benefits in in vitro and in vivo models of neurodegenerative diseases through modulating a variety of pathogenic mechanisms, including neuroinflammation, autophagy, mitochondrial dysfunction, and the abnormal phosphorylation of pathognomonic proteins

Weight loss becomes harder with hypothyroidism, but GLP-1 medications like semaglutide can still help when thyroid levels are managed

Individuals achieving 5% weight loss from baseline body weight had significantly lower AF incidence (OR 0.83, 95% CI 0.780.89), whereas no significant differences were observed in those with no weight loss or weight gain (OR 1.05, 95% CI 0.971.12)

This article reviews the efficacy and safety of different strategies to initiate and intensify basal insulin, with focus on new fixed ratio combinations of basal insulin with GLP-1 RAs available for use in a single injection pen (insulin degludec/liraglutide and insulin glargine/lixisenatide).