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For example, SHP2 inhibitors can suppress KRAS G12C GTPase activity and enhance the effects of G12C inhibitors, which are currently being trialed in combination with Sotorasib (NCT04185883) and other KRAS G12C inhibitors

*Correspondence: Kathrin Eller [email protected] This article was submitted to Nephrology, a section of the journal Frontiers in Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

(1) Al-Naggar IMA, Kuchel GA, Xu M

Degradation to the particles can also result in reduced resin lifetimes

This polymorphism is in intron 13 of the MAO-B gene and is thought to disrupt monoamine metabolism, leading to increased ROS production and oxidative stress within the central nervous system (Leko et al., 2021)

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