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Description
Mechanistically, V-9302 sustained glutamine uptake by CD8 + T cells, by promoting the compensatory upregulation of the glutamine transporter ATB 0,+ / Slc6a14 , in CD8 + T cells, to support de novo glutathione synthesis and improve redox balance in T cells
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2021;10 doi: 10.3390/antiox10091474
Systemic toxicity evaluationssuch as hematological parameters, biochemical profile, and organ histopathologyare also emphasized, as abnormality of these can occur via intravenous injection, a standard route of administration, for drug nanoparticles in the treatment of AD (Ma et al., 2021
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10.3233/JND-230123 111 McDonaldD
