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Laugh lines are caused by the repetitive motion of smiling

Although the exact molecular mechanisms behind this relationship remain to be elucidated, multiple studies have suggested that dietary TMAO promotes atherosclerosiswhich can lead to coronary artery disease if left uncheckedvia a combination of poor metabolic control (specifically, glucose intolerance and insulin resistance), overexpression of inflammatory markers 1 , and altered bile acid metabolism 10

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[DOI] [PubMed] [Google Scholar] Kellogg E