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Moreover, NQO1 has been shown to modulate the redox state of various transcription factors, such as p53, AP-1, and Nrf2, thereby influencing the expression of diverse genes implicated in cell cycle control, apoptosis, and antioxidant defense

The published research literature has investigated: Gene expression modulation across hundreds of genes (documented in microarray studies) Collagen synthesis and skin remodeling Tissue protection through antioxidant and copper-dependent mechanisms Wound healing and dermatological research Various aging-related cellular processes The mechanisms don't overlap meaningfully

Sun, W.-N

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Transcriptional Regulation of Ascorbic Acid During Fruit Ripening in Pepper (Capsicum annuum) Varieties with Low and High Antioxidants Content

[DOI] [PMC free article] [PubMed] [Google Scholar] Brown SW, Meyers RT, Brennan KM, Rumble JM, Narasimhachari N, Perozzi EF, Ryan JJ, Stewart JK, Fischer-Stenger K (2003) Catecholamines in a macrophage cell line