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In cell culture studies, the knockdown of specific enzymes that synthesize GSH did cause both a decrease in GSH and the VD metabolism genes statuses, and L-cysteine supplementation simultaneously caused an improvement in both GSH and VD metabolism genes [3]
Elife 6 , (2017)
In addition, the enzyme expression pattern from the GeneCard database ( also suggests a similar pattern of expression among the family members, with maximum similarity in expression patterns in the case of GSTM1 and GSTM2 in different tissues
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doi: 10.2337/dc16-2042 6 CortezMSingletonJRSmithAG
