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These results suggest that lactate facilitates macrophage reprogramming toward a suppressive and tissue-repairing phenotype in response to injury

Evolution and phylogenetic distribution of SLC22A4 Phylogenetic analyses (201,202) indicate that homologues of SLC22A4, a relative of the major facilitator superfamily 2, exist only in vertebrate animals, especially mammals, birds and fish, with occasional examples in reptiles (for example, Xenopus spp.)

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DAT and NET both transport AMPH, although NET has an approximate 1.5-fold higher apparent affinity (Table 1)

We will discuss how inflammation, aging, dysbiosis and metabolic diseases can affect intestinal barrier-bone link