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doi: 10.3389/fnagi.2015.00058 Received 26 January 2015 Accepted 05 April 2015 Published 21 April 2015 Volume 7 - 2015 Edited by Marta Magarinos, Universidad Autonoma de Madrid, Spain Reviewed by Gilda Kalinec, University of California, Los Angeles, USA

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Quick Takeaways BPC-157 activates FAK-paxillin pathways that cancer cells use for invasion and metastasis The peptide promotes angiogenesis through VEGFR2, a receptor dysregulated in half of human cancers No published human study has tracked cancer incidence or tumor progression with BPC-157 use Animal studies show neither tumor reduction nor runaway growth, leaving cancer risk uncertain What BPC-157 Does in the Body BPC-157 is a synthetic 15-amino-acid peptide originally isolated from human gastric juice

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This will contribute to evidence-based recommendations for its use

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Biomedicines, 9(10), 1300.

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