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This phenomenon is closely associated with enhanced activation of antioxidant-responsive promoters and transcription factors, particularly the well-known HO-1 regulators AP-1 and NFB (Lavrovsky et al., 1993

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Glutathiones presence is critical to counteract these effects

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8 Toxicity and side effects The toxicological problems associated with herbal medicines are a major public health issue

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(B) Western blot of Tns3 in total cell lysates from indicated cells

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Kwak et al., 2001

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Post-mortem human studies confirmed this mechanism, demonstrating elevated GFAP, MAO-B and GABA expression in reactive astrocytes within the temporal cortex, with a strong correlation between GFAP and MAO-B levels 345

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