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TZDs activate PPAR to promote adipogenesis and fatty acid uptake, increase glucose utilization and decrease glucose production, and subsequently enhance insulin sensitivity by upregulating genes involved in lipid metabolism, such as CD36, FABP4 , and LPL (395)
The protocol was approved by an external Institutional Review Board (IntegReview
Glycolytic lactate and mitochondria-derived CO 2 are the primary contributors to the proton efflux rate (PER), leading to extracellular acidification
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doi: 10.1186/1750-1172-7-32 [PubMed] 25950372 Ghannoum M, Lalibert M, Nolin TD, MacTier R, Lavergne V, Hoffman RS, Gosselin S
