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Description
Around a quarter of patients exhibit high expression of the human epidermal growth factor receptor 2 (HER2, also known as ERBB2) as a result of gene amplification or mutation [2, 3]

As a result, it promotes CREB1 transcription and M2 macrophage polarization

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The acuity of life-threatening sepsis suggests that metabolic modulation may be a promising avenue for therapy

[94] Clinical Diagnosis: Repeated sun exposure promotes the development of recurrent blisters and erosions, with secondary infections that may result in severe scarring, sclerodermatous change, and deformities of the hand.[95] Sclerodactyly, osteolysis and shortening of the phalanges, and progressive joint deformities can occur as well

Bensadoun JC
