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DAMPs In innate immunity, pattern recognition receptors (PRR) can recognize and bind with ligands on antigens or damaged host cells, inducing immune and inflammatory responses

Key idea: Thiamine deficiency can both follow gut problems and worsen them

The thiolate cysteine sulphur then reacts with any reactive electrophile, which is able to dock in its own turn to the appropriate site of the enzyme

We noticed that secretory progenitors, goblet cells and deep crypt secretory cells (DCS) (Leiden clusters 0 and 2) were not clearly distinguishable, as they showed heterogeneous expression profiles

Epigenetics: poly(ADP-ribosyl)ation of PARP-1 regulates genomic methylation patterns

polyphenols using an in vitro human digestion model and evaluation of their antimicrobial activity