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In summary, protein acylation of metabolic enzymes or nutrient transporters always modulate the progression of different diseases by regulating glucose, fatty acid and amino acid metabolic reprogramming

Results We found that ALCAR reduces cell proliferation, induces apoptosis, hinders the production of pro inflammatory cytokines (TNF- and IFN-) and of chemokines CCL2, CXCL12 and receptor CXCR4 involved in the chemotactic axis and impairs the adhesion, migration and invasion capabilities of PCa and BPH cells in vitro

doi: 10.1186/1475-2891-13-79, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 63.Pagano G, Manfredi C, Pallard FV, Lyakhovich A, Tiano L, Trifuoggi M

Prague Med Rep

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