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The assay can be used to measure CAT activity in plasma, serum, erythrocyte lysates, tissue homogenates, and cell lysates [10,11]

In vivo studies have shown that excess lactate from astrocytic glycolysis disrupts synaptic plasticity and accelerates A aggregation, exacerbating cognitive impairment in APP/PS1 mice [114]

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Patients with hyperoxaluria are at a higher risk of vascular dysfunction, including hypertension and atherosclerosis

Substantial variability emerged among individual agents: exenatide demonstrated the longest median latency (54 days, IQR 16184), while dulaglutide showed the shortest (7 days, IQR 234)

Those who started on a placebo and switched to Kesimpta in the extension trial also experienced pronounced reductions in their relapse rates and MRI lesions, and their NEDA-3 rates increased after switching as well