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This age-related NAD+ depletion impairs mitochondrial energy production, reduces SIRT1 activity, compromises DNA repair mechanisms, and accelerates cellular senescence

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Interfering with their use of it (through drugs called glutaminase inhibitors) could be a potential treatment approach

Its continued presence within scientific literature has established AOD-9604 as a recognised research compound across multiple areas of peptide science

Systemic side effects may occur in some individuals