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Mitochondrial disorders: Research reveals that CVS biomarkers in children overlap with those seen in mitochondrial disorders

Naturally, ALA is found in mitochondria where it binds to the E2 subunit and is used as a cofactor for both pyruvate dehydrogenase (PDH) and -ketoglutarate dehydrogenase complexes [18]

Moreover, children with cleft lip and palate are reported to have more feelings of anger, sadness, fear and alienation from their peers
