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Also, IGFBPrPs have been associated with insulin resistance and fasting glucose levels [179, 180]

A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American Heart Association

doi: 10.1016/j.lfs.2020.117788

As illustrated in Figure 3, GPS has been shown to elevate the levels of key growth factors, including vascular endothelial growth factor (VEGF) and transforming growth factor-beta (TGF-)

33 Oxidative stress is associated with the pathophysiology of cardiovascular diseases (CVDs), while antioxidants are involved in neutralizing ROS and protecting against oxidative stress