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Moreover, ICH guidelines were carried out to validate the adopted method
Though IV and oral NAC loading doses were similar (140-150 mg/kg), the oral NAC regimen provided an additional 70 mg/kg every 4 hours for 17 doses, while the IV NAC regimen provided an additional 12.5 mg/kg/h for 4 hours, followed by 6.25 mg/kg/hr for the next 16 hours
this observation suggests that inactivation of the GPx3 gene by hypermethylation of the promoter may contribute to breast cancer progression
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More alcohol in your drink = higher BAC
