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Rare, mild to moderate AEs Nausea, epigastric discomfort, vomiting (unclear

Primary pain in ALS includes neuropathic pain and pain due to spasticity or cramps, whereas secondary pain is mainly nociceptive and may appear as muscle weakness and atrophy progress [83]

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Subgroup-analysis on the VAS Scores by Subdividing RCTs according to the Route of Administration

False discovery rate (FDR) control was applied using the BenjaminiHochberg method at a threshold of 0.1

Clinical trial research supports this, suggesting that ALC can offer more extensive health benefits compared to L-carnitine