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We assess and optimize: Surface charge (cationic, anionic, neutral) Physical stability over time (aggregation, leakage, fusion) Thermal and pH stability (4) Release Profiles Liposomes can be designed for immediate release, delayed release, or stimuli-responsive delivery (e.g., pH-sensitive or temperature-sensitive systems)

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4.1 Enzymatic pathway of ferroptosis 4.1.1 ACSL4/LPCAT3/LOX lipid metabolism pathway Among the three families of lipid oxidases, lipoxygenase is crucial to the enzymatic processes driving ferroptosis

These nutrients help regenerate and support glutathione levels in the body, improving antioxidant activity and overall cellular protection