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How AOD-9604 Works at the Cellular Level AOD-9604 exerts its fat-reducing effects through activation of beta-3 adrenergic receptors located predominantly in adipose (fat) tissue

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The first 1 mg engages more of the GIP receptor than the next 11 mg combined

declares having received honoraria from Novo Nordisk, Eli Lilly, Akebia Therapeutics, Ardelyx, Becton Dickinson, Endologix, FibroGen, GSK, Medtronic, Neovasc, Provention Bio, ReCor, BrainStorm Cell Therapeutics, Alnylam and Intarcia for consulting activities, and research funding to his institution from AbbVie, Esperion, AstraZeneca, CSL Behring, Novartis and Eli Lilly