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This is why storing vials in the refrigerator door is risky

This is completely normal and does not indicate damage, contamination, or reduced quality

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Not only does the resulting barrier disruption promote diarrhoea because of increased water concentration in the intestinal lumen, but there is also a greater opportunity for the development of secondary infections due to deeper tissue penetration by other pathogens and toxins (Guttman and Finlay 2009)

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Future studies will be focused on optimizing the MQ-scaffold lead series to generate more potent NNMT inhibitors with significantly improved drug-like ADME profile