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OMIM, phenotype MIM number #300100) is the most common inherited peroxisomal disorder

It has been reported that administration of concentrated NGF and GDNF to rats resulted in increased Schwann cell proliferation and improved functions [25]

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In addition to stimulating adrenocorticotropic hormone (ACTH) release from the pituitary and the cascade of events leading to glucocorticoid release, CRH is also released into the arcuate nucleus of the hypothalamus (ARC) to inhibit neuropeptide Y (NPY)/agouti-related peptide (AGRP) neurons there (Richard et al., 2002)