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5-Amino-1MQ is a small molecule studied for its role as an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme linked to metabolic regulation and cellular energy balance

Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics

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Considering this challenge, we hope that the presented tools will empower general practitioners working in a variety of settings to accelerate differential diagnosis for this group of metabolic disorders

Also, its deficiency can result in high levels of homocysteine in the blood which may have direct effects on the neurotransmitters implicated in depression

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