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Thus, many studies have explored WM alterations in aging brains and have identified WM atrophy (Lemaitre et al., 2005), WM tract disruption (Shenkin et al., 2005), vessel impairments (Pantoni, 2002), increased inflammation (Sloane et al., 1999), and loss of myelination (Marner et al., 2003)

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10.1016/j.canlet.2025.217676 11 ArkanC.Akcora-YildizD