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Individualized titration is essential to achieve serum trough levels in the mid-normal physiologic range, thereby minimizing adverse effects such as erythrocytosis, gynecomastia due to aromatization, or suppression of endogenous spermatogenesis

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The original data are published monthly by the NHS and this facilitates future updates to monitor further changes in prescribing

The vial should be stored in a cool dark area, not in direct sunlight