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Journal of Microscopy (2010)

10.1155/2022/7043856 175 YangY.ZengQ.GaoJ.YangB.ZhouJ.LiK.et al (2022b)

Moreover, it is not known if S-5-HT mediated the effects of L-carnitine on fatigue, as it is possible that L-carnitine could have effects unrelated to S-5-HT that could reduce fatigue and in parallel promote increased synthesis of peripheral 5-HT

[73] found that the methotrexate is known to cause hepatic fibrosis in some patients, which might progress to cirrhosis

Conversely, there is no evidence for accumulation of valproyl-CoA in brain tissue, suggesting that the effects of VPA in the CNS are independent of the formation of this metabolite [80]