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It is this breadth of documented laboratory activity that makes it particularly relevant across multiple research disciplines

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Additionally, liver disease may increase production or release of haptocorrin itself, further elevating total B12 measurements even when functional B12 delivery to tissues may be impaired

[DOI] [Google Scholar] Schmitt RG, Hirt RC

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This suggests that combined treatment with EGFR and c-MET inhibitors could be necessary in a subset of patients to circumvent the onset of resistance to these drugs