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Crystallisation was performed in the dark using the sitting drop vapour diffusion technique (200 nL crystallisation reagent mixed with 200 nL protein)

These biologically relevant sources of DSBs have diverse end structures, varying from ends that can be directly ligated to more complex end structures that must first be processed by a variety of factors that include polymerases, end-cleaning enzymes, and nucleases (reviewed in ref

Taking the tablet with a meal can reduce the chance of stomach upset, and dietary fat may help absorption of vitamin E

Diagnostic interview for genetic studies

PMC10643103 Gupta AK, et al