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Treatment with multi-strain probiotic VSL#3 did not appear to reduce the elevated TMAO level in plasma caused by a high-fat diet ( Streptococcus thermophilus , Lactobacillus acidophilus , and Bifidobacterium longum ) for 3 months, there was no change in TMAO level, but the betaine level in plasma was significantly increased (Table 1) ( TABLE 1 Probiotic/prebiotic that effect TMAO level

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A 2013 study, which included both rodents and 2,595 people who underwent elective cardiac evaluation, found that L-carnitine is converted to trimethylamine N-oxide (TMAO) via gut microbiota

Montauti E, Oh DY, Fong L

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10.1002/ajmg.a.30524 110