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Control rats with the ligated superior mesenteric vein and artery regularly showed a poor presentation (Figure 5), and they responded with rapid rupture of the superior mesenteric vein or without a sign of the superior mesenteric artery

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The MD Anderson algorithm intentionally adopts a stepped-care approach for VEGFi-related hypertension to reflect the unique clinical context of oncology patients, in whom VEGFi regimens may involve on-off treatment cycles and may also change rapidly based on therapeutic response or toxicity

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