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Chronic central neuropathic pain, resulting from disease or damage to the central somatosensory nervous system, covers pain related to spinal cord or brain injuries, post-stroke pain, and pain associated with multiple sclerosis [10]

L., Edwards, R

They also prevent dehydration, boost energy, and support overall wellness

In this regard, utilizing more representative larger animal models (e.g., non-human primates, swine, ferrets) in parallel with rodents for intranasal delivery research could improve the predictive value of preclinical studies

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However, its oral bioavailability has long been debated, prompting the development of enhanced delivery formats like liposomal glutathione or sublingual tablets