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However, if left untreated, the condition can cause severe, long-lasting damage to the heart and brain, as well as other organs

10.1016/j.bcp.2020.114365 53 NoblancA.PeltierM.Damon-SoubeyrandC.KerchkoveN.ChaboryE.VernetP.et al (2012)

This is where we must consider bioavailabilitya term we use to describe how well a nutrient is actually absorbed and utilised by the body

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Center SA, Guida L, Zanelli MJ

Since the therapeutic use of TQ is limited by its poor bioavailability, strategies, such as purposeful modification of its structure without hindering biological activity, may improve its bioavailability

*New patients only, or those who have not been in for at least 6 months