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Over time, the brain tolerates these substances, requiring higher doses to achieve the same effect

[DOI] [PMC free article] [PubMed] [Google Scholar] 242.Poboy K., Poboy T., Domaski P., Derczyski M., Konarski W., Domaska-Poboa J

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These cross peaks show the nuclear spins that are connected through magnetization transfer i.e
