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Heads up: COMT interaction Your genotype for COMT rs4680 is , which means your connected data file indicates slow COMT function

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Stamler JS, Osborne JA, Jaraki O, Rabbani LE, Mullins M, Singel D, and Loscalzo J (1993)

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After binding to TGR, NADPH donates electrons from its nicotinamide ring to FAD interacting with TGR with its isoalloxazine ring and the nearby C154/C159 redox couple [10,26] for transferring the electrons first to the C596/U597 redox couple on the C-terminal segment of the neighboring subunit, and then to the oxidized Trx or the C28/C31 redox couple of the neighboring monomer to reduce GSSG (S1 Table) [10,26,27]