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Med Rev (2021)

In summary, through pan-cancer analysis using the TIMER database combined with mechanistic integration, this review demonstrates that the activation patterns of the serine synthesis pathway (SSP) in malignant tumors are not randomly distributed, but follow three distinct molecular subtypes: driver mutation-dependent, microenvironmental stress-adaptive, and epigenetic dysregulation subtypes

10.1111/nph.15550 [DOI] [PubMed] [Google Scholar] Nigam M, Punia B, Dimri DB, Mishra AP, Radu A-F, Bungau G (2025) Reactive oxygen species: a double-edged sword in the modulation of cancer signaling pathway dynamics

and Freude K., Astrocytes: The Stars in Neurodegeneration?, Biomolecules 14, no

As discussed in Section 2.3, this pathway is influenced by oxidative stress and plays a protective role in the acute phase by promoting cardiomyocyte survival and upregulating anti-apoptotic and antioxidant proteins (Liu P