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3.1.3 EVs regulate the insulin pathway and liver metabolism, affecting insulin resistance Insulin resistance refers to the decreased sensitivity of the body to insulin, leading to a reduced efficiency in insulins promotion of glucose uptake and utilization

change in CARS ( r = 0.43) and average PGI-R 2 ( r = 0.40), suggesting the older participants improved somewhat more, but there was no correlation of adjusted age vs

Samuelov L, Kinori M, Bertolini M, Paus R

The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells

Long-term studies are ongoing to confirm efficacy and safety (Bachelez 2015)

Their primary applications are in managing type 2 diabetes and obesity due to their effects on insulin secretion, glucagon suppression, and appetite