action of glp 1 agonist Glucagon-like peptide receptor agonists: cardiovascular benefits and mechanisms Mechanism of action of GLP-1

- **Slow digestion:** Delaying stomach emptying to prevent spikes in sugar levels after meals

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When you're on a GLP-1, the digestive challenges can be so frustrating and uncomfortable

Five clinical trials in type 2-diabetic subjects (SURPASS 15) have shown that tirzepatide at 515 mg per week reduces both HbA1c (1.24 to 2.58%) and body weight (5.411.7 kg) by amounts unprecedented for a single agent

It has a natural yellow pigment (dye) which also shows as bright yellow fluorescence under UV light.

Interestingly, glucagon-like peptide-1 receptor agonists (GLP-1RAs), used in the treatment of T2DM and obesity, are known to show pro-cognitive and neuroprotective properties, and exert modulatory effects on immune, endocrine and metabolic processes in the central nervous system